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Click below to read about the progress of projects supported
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| Harold Seeley, Anne Bown-Seeley, Andrew and Sarah Cox
(Imperium Capital Group) with Deb Stringer of the Cancer Council Victoria (centre) Photos: Andrea Russell |
TUXEDO JUNCTION 2008
Salutes The Musicals
Grant Recipients
The Board and Producers of Tuxedo Junction 2008 take great pleasure in announcing the recipients of the funds raised
at Tuxedo Junction on the 9th of August. Naming Rights for the two grants were purchased by our generous supporters: Harold Seeley AM, Anne Brown-Seeley - the Seeley Gratitude Grant to God and, Andrew and Sarah Cox - the Imperium Capitol Group Grant. Tuxedo Junction could not take place without the support of many companies and individuals who share the board and working parties’ vision.
These grants are given because of your commitment and simply because you put your time, money and energy into
Tuxedo Junction 2008.
Please note: the research projects below will be partially funded by the following grants.
THE TUXEDO JUNCTION 2008 GRANT
At this years event Melanie Nightingale, representing our Corporate Partners salesforce.com, invited all guests to list the names of their family and friends who have been touched by cancer on a whiteboard. Everyone who saw the board on the night was touched deeply by the number of names listed. From the 320 guests and staff in the room there were over 150 names. The Board and Producers of Tuxedo Junction take great pride in honouring those listed by attaching these names to The Tuxedo Junction 2008 Grant.
Loved ones touched by Cancer
| Ada Milaic | Adrienne Sweeney | Alan Keys | Alanah Gray | Albert O'Brian |
| Alex Millar | Alf Ryland | Andre Crois | Angie McClusky | Anne Lyle Dupre |
| Annette Burton | Arthoro Pacquola | Barbara Buss | Barbara Qukk | Barbara Shea |
| Benjamin Lindner | Bernard Paynter | Betty Harris | Bev Knight | Beverly Heffernan |
| Bluey O'Neil | Bob D'Argauille | Bonzo Bota | Brian Kirk | Brian Clarke |
| Butch Rip | Carmel Ross | Carolyn Schuegel | Carmel Ross | Chris Crichton |
| Colin Croff | Corinne Cousin | Cynthia Edwards | Daphne Nicol | Dino Vidotto |
| Eddy Dowey | Edith Kirk | Evelyn Taylor | Faye Lee | Fiona Cox |
| Fred Camilleri | George Vitis | Gerda Vorkuef | Gordon David Jennings | Graeme Harris |
| Graham Ward | Harry Holling | Helen Hally | Helena Lee | Hilda Ross |
| Ian D Fuller | Ian Lappen | Inge Vorkuef | Jackie Cooke | Jeff Ingham |
| Jenny Hales | Jenny Long | Jill Enay | Jill Ramle | Joan Viulers |
| Joe Sandry | John Mawer | John Shea | Josie West | Joyce Sedgman |
| Julene Blacksell | Julie Miller | Karen Graves | Karina Brammer | Kate Waters |
| Ken Dowling | Laan Edwards | Len Allen | Len Dennant | Lily Casiby |
| Lindy Bok | Liz Bartlett | Liz Kaehne | Lucas (age 5) | Luigi Pacquola |
| Lyn Read | Lyn Sahr | Mabel Normington | Madeline Pepperell | Majory Clarke |
| Malcom Shaddick | Manfred Slotnoni | Marg Fannings | Margaret Sisson | Marie Hobday |
| Martin Ries | Mary Bdekers | Mary Fiorio | Mary Szegedi | Mary Warren |
| Maryann Kezy | Mathew Pepperell | Max Officer | Maxwell Ramsey | Michael Baron |
| Michael Moul | Michael Nolan | Michelle Jackson | Milada Delalic | Myken Martens |
| Murray James | Nancye Welch | Natasha Vorkuef | Pamela Irving | Pat Sisson |
| Patricia Mary Simondson | Paul Beady | Paul Jung | Peter Cousin | Peter Shea |
| Peter Thompson | Phoebe Lindner | Pierina Vidotto | Rae Martens | Ralfe Taylor |
| Ray Neill | Rene Butler | Rhonda Yoze | Robyn K Stolfo | Rod Bdekers |
| Rod Groves | Ruth Staples | Sam Toovey | Sean Dineen | Sergio Veskovi |
| Shirley Pepperell | Sophie Doro | Stephen Jones | Steve Berry | Sue Aqua |
| Sue DeReuter | Sue Pepperell | Susan Crawshaw | Svellen Campbell | Sylvia Jones |
| Theresa Derore | Thomas Szegedi | Tina Clarke | Tony Camilleri | Trish Coulton |
| Trish Foro | Trudy Shepheard | Veronica Szeremna | Vilma Schokman | Wayne Osler |
Dr David Thomas: A/Prof Paul Simmons Peter MacCallum Cancer Centre
Bone Cancer: Research into the causes of bone cancer in adolescents
Osteosarcoma is the most common primary bone cancer and the third most common cancer in adolescents. Treatment often entails aggressive surgery with intensive chemotherapy, and causes life-long morbidity. The 5-year survival of patients with metastatic or recurrent disease is less than 25%. Using cell lines and primary normal human bone cells,
we will knockdown expression of WIF1 and examine whether these cells can undergo normal development. We will
also examine how re-expressing WIF1 in bone cancer cells or treatment with WIF1 protein affects cancer cell growth
and survival.
THE SEELEY GRATITUDE TO GOD GRANT
Harold and Anne Seeley say they are contributors to this grant out of hearts full of gratitude to God for their own health
and the health of their 41 children and great grandchildren.
Dr Weisan Chan: Ludwig Institute for Cancer Research
Melanoma: Research on the prevention, early detection and treatment in adults
Most tumour cells express tumour-specific proteins. Killer T cells suppress and eliminate tumour cells by recognising fragments (epitopes) derived from these tumour proteins. For some poorly understood reasons, these cells can either
fail to activate or be rendered irresponsive during tumour genesis. A major goal of cancer vaccine is to either activate these T cells or reverse their unresponsiveness.
Prof Geoffrey Pietersz: Macfarlane Burnet Institute for Medical Research and Public Health
Breast cancer: Research into the prevention of breast cancer
We have designed a vaccine based on a unique delivery system. We will now design a vaccine that has multiple peptides so that people can make killer cells. Cancer cells are constantly changing to avoid detection by the immune system; we now would like to produce a vaccine which is more effective and will benefit everyone.
Doreen Ackerman: Cancer Council Hotline
4 Rural Workshops: When Cancer Won't Go Away
People living in rural areas (who have a worse outcome when they are diagnosed with cancer) can access the Cancer Helpline and online support groups.
These free forums provide people with advanced cancer, and their friends and families, the chance to speak with others in similar situations. Topics covered include financial and legal issues, and current treatments and different medical supports available for advanced cancer. Questions answered will also include what happens when a person presents with an advanced cancer diagnosis. The Family Issues and Living With Uncertainty session is conducted by a psychologist, who talks about coping with cancer and living with uncertainty.
THE IMPERIUM CAPTIOL GROUP GRANT
Dr David Thomas, A/Prof Paul Simmons: Peter MacCallum Cancer Centre
Bone Cancer: Research into the causes of bone cancer in adolescents
Osteosarcoma is the most common primary bone cancer and the third most common cancer in adolescents. Treatment often entails aggressive surgery with intensive chemotherapy, and causes life-long morbidity. The 5-year survival of patients with metastatic or recurrent disease is less than 25%. Using cell lines and primary normal human bone cells,
we will knockdown expression of WIF1 and examine whether these cells can undergo normal development. We will also examine how re-expressing WIF1 in bone cancer cells or treatment with WIF1 protein affects cancer cell growth and survival.
A/Prof Erik Thompson, A/Prof Alexander Dobrovic, Prof Peter Choong, Dr Prue Hill, A/Prof Michael Henderson, Prof Klaus Pantel: University of Melbourne
Breast Cancer
Epithelial carcinoma cells undergo epithelial mesenchymal transition (EMT) to induce migration, invasion and survival, enhancing cancer spread. Disseminated cancer cells need a reverse transition (MET) to form a new mass. We will examine EMT / MET status of cells at different stages of metastasis in patients, whether silencing by promoter methylation drives these transitions, and the effect of forcing epithelial / mesenchymal states on breast cancer dissemination.
